Effect of non condensable gases (NCGs) on steam sterilization process
Steam Sterilization process is defined as the action of exposing dry, saturated steam on the product to be sterilized for a specified time period under high pressure. This kills off all living microorganisms. In medical and pharmaceutical fields, the steam is produced from purified water which has to comply with the limit values of the EP/USP.
- Insufficient energy delivered to the load to sterilize. Gases do not deliver the same latent heat energy as steam.
- Pockets of gas can form that provide “islands” of un sterility. Unless the indicator is in such an island, their presence will go undetected.