|
Narrow Therapeutic Index (NTI) Drugs |
|
Therapeutic Index : A ratio that compares the blood concentration at
which a drug becomes toxic and the concentration at which the drug is
effective. The larger the therapeutic index (TI), the
safer the drug is. |
Examples of NTI drugs includes,
aminoglycosides, ciclosporin, carbamazepine, digoxin, digitoxin, flecainide,
lithium, phenytoin, phenobarbital, rifampicin, theophylline and warfarin
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