Wednesday, 22 February 2012
Why Isopropyl Alcohol is Widely Used As a Hand Disinfectant in Pharma?
Isopropyl alcohol will instantly kill 99.99 percent or more of all non-spore forming bacteria in less than 30 seconds, both in the laboratory and on human skin. Iso propyl alcohol is acceptable in pharmaceuticals because they do not leave any residues after drying.The disinfection activity of isopropyl alcohol is significantly lower at concentrations below 50% and is optimal in the 60 - 90% range.
Isopropyl alcohol have lipophilic properties and can cause membrane damage and rapid denaturation of proteins,with subsequent interference with metabolism and cell lysis.
Isopropyl alcohol is not sporicidal.But it can inhibit sporulation and spore germination.